Autoreactivity in HIV-1 broadly neutralizing antibodies
نویسندگان
چکیده
منابع مشابه
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.
The design of a human immunodeficiency virus-1 (HIV-1) immunogen that can induce broadly reactive neutralizing antibodies is a major goal of HIV-1 vaccine development. Although rare human monoclonal antibodies (mAbs) exist that broadly neutralize HIV-1, HIV-1 envelope immunogens do not induce these antibody specificities. Here we demonstrate that the two most broadly reactive HIV-1 envelope gp4...
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ژورنال
عنوان ژورنال: Current Opinion in HIV and AIDS
سال: 2014
ISSN: 1746-630X
DOI: 10.1097/coh.0000000000000049